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atcc 35915  (ATCC)


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    Structured Review

    ATCC atcc 35915
    Atcc 35915, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/atcc+35915/Ruminococcus+torques/pm41448471-208-4-4
    Average 93 stars, based on 3 article reviews
    atcc 35915 - by Bioz Stars, 2026-10
    93/100 stars

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    Related Articles

    Bacteria:

    Article Title: Polypeptides synthesized by common bacteria in the human gut improve rodent metabolism.
    Article Snippet: .. Potential virulence-associated factors in the genomes of RT strains ATCC 27756 and ATCC 35915 were identified through homology mapping against the core dataset of the Virulence Factors of Pathogenic Bacteria (VFDB)37, using NCBI BLASTn (version 2.12.0). .. The search for potential proteases and peptidases in the genome of RT ATCC 27756 was carried out using the MEROPS database38.

    Article Title: Polypeptides synthesized by common bacteria in the human gut improve rodent metabolism
    Article Snippet: .. Potential virulence-associated factors in the genomes of RT strains ATCC 27756 and ATCC 35915 were identified through homology mapping against the core dataset of the Virulence Factors of Pathogenic Bacteria (VFDB) , using NCBI BLASTn (version 2.12.0). .. The search for potential proteases and peptidases in the genome of RT ATCC 27756 was carried out using the MEROPS database .

    Over Expression:

    Article Title: Challenges and recent progress in ursodeoxycholic acid production
    Article Snippet: .. Zheng et al. [55] discovered a new 7β-HSDH from Ruminococcus torques ATCC 35915 in 2017, named 7β-HSDHRt, and studied its enzymic properties via heterologous overexpression in E. coli. ..

    Cloning:

    Article Title: Large-scale production of ursodeoxycholic acid from chenodeoxycholic acid by engineering 7α- and 7β-hydroxysteroid dehydrogenase.
    Article Snippet: 7αand 7β-hydroxysteroid dehydrogenases (HSDHs) are key biocatalysts for the biotransformation of ursodeoxycholic acid (UDCA) from chenodeoxycholic acid (CDCA).. Various researches focused on heterogeneously expressed engineering enzymes to epimerize CDCA for UDCA, however not yet applied to further industrial application.. In this work, we present the large-scale production of UDCA from CDCA by 7αand 7β-HSDH enzymatic synthesis.

    Expressing:

    Article Title: Large-scale production of ursodeoxycholic acid from chenodeoxycholic acid by engineering 7α- and 7β-hydroxysteroid dehydrogenase.
    Article Snippet: 7αand 7β-hydroxysteroid dehydrogenases (HSDHs) are key biocatalysts for the biotransformation of ursodeoxycholic acid (UDCA) from chenodeoxycholic acid (CDCA).. Various researches focused on heterogeneously expressed engineering enzymes to epimerize CDCA for UDCA, however not yet applied to further industrial application.. In this work, we present the large-scale production of UDCA from CDCA by 7αand 7β-HSDH enzymatic synthesis.

    Purification:

    Article Title: Large-scale production of ursodeoxycholic acid from chenodeoxycholic acid by engineering 7α- and 7β-hydroxysteroid dehydrogenase.
    Article Snippet: 7αand 7β-hydroxysteroid dehydrogenases (HSDHs) are key biocatalysts for the biotransformation of ursodeoxycholic acid (UDCA) from chenodeoxycholic acid (CDCA).. Various researches focused on heterogeneously expressed engineering enzymes to epimerize CDCA for UDCA, however not yet applied to further industrial application.. In this work, we present the large-scale production of UDCA from CDCA by 7αand 7β-HSDH enzymatic synthesis.

    Modification:

    Article Title: Large-scale production of ursodeoxycholic acid from chenodeoxycholic acid by engineering 7α- and 7β-hydroxysteroid dehydrogenase.
    Article Snippet: 7αand 7β-hydroxysteroid dehydrogenases (HSDHs) are key biocatalysts for the biotransformation of ursodeoxycholic acid (UDCA) from chenodeoxycholic acid (CDCA).. Various researches focused on heterogeneously expressed engineering enzymes to epimerize CDCA for UDCA, however not yet applied to further industrial application.. In this work, we present the large-scale production of UDCA from CDCA by 7αand 7β-HSDH enzymatic synthesis.

    Sequencing:

    Article Title: Large-scale production of ursodeoxycholic acid from chenodeoxycholic acid by engineering 7α- and 7β-hydroxysteroid dehydrogenase.
    Article Snippet: 7αand 7β-hydroxysteroid dehydrogenases (HSDHs) are key biocatalysts for the biotransformation of ursodeoxycholic acid (UDCA) from chenodeoxycholic acid (CDCA).. Various researches focused on heterogeneously expressed engineering enzymes to epimerize CDCA for UDCA, however not yet applied to further industrial application.. In this work, we present the large-scale production of UDCA from CDCA by 7αand 7β-HSDH enzymatic synthesis.

    Construct:

    Article Title: Recent advances in structure-based enzyme engineering for functional reconstruction.
    Article Snippet: Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, Zhejiang, People's Republic of China Engineering Research Center of Bioconversion and Biopurification of the Ministry of Education, Zhejiang University of Technology, Hangzhou, Zhejiang, People's Republic of China The National and Local Joint Engineering Research Center for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, Zhejiang, People's Republic of China

    Mutagenesis:

    Article Title: Recent advances in structure-based enzyme engineering for functional reconstruction.
    Article Snippet: Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, Zhejiang, People's Republic of China Engineering Research Center of Bioconversion and Biopurification of the Ministry of Education, Zhejiang University of Technology, Hangzhou, Zhejiang, People's Republic of China The National and Local Joint Engineering Research Center for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, Zhejiang, People's Republic of China

    other:

    Article Title: Engineering 7β-HSDH_Osp for enhanced catalytic efficiency: Advancing sustainable biosynthesis of ursodeoxycholic acid.
    Article Snippet: • A quintuple mutant of 7β-HSDH_Osp achieved 6.79-fold higher specific activity (65.18 U⋅mg 1) than wild-type.. • Enhanced catalytic efficiency and substrate affinity with stronger binding (ΔG = –13.18 kcal⋅mol 1) and flexibility.. • Broad pH stability (6.5–10.0) enabled by key lysine residues and a unique lowpKa cysteine (C93).



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